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Importance of blood typing
In horses there are 7 blood group systems (A,C,D,K,P,Q,U) with greater than 30 red blood cell factors. Of these, Ca seems to be one of the most immunogenic antigens (causing allo-immunization).
Blood typing before transfusion minimizes the risk of transfusion reactions and prevent immunization of the recepient against incompatible RBC antigens. Ca, Aa and Qa antigens are clinically important for their role in transfusion reactions.
Neonatal isoerythrolysis (NI)
NI is a potentially fatal condition in new foals that result from an incompatibility of blood types between the mare and the foal. It is caused when the mare produces antibodies against the foal RBC and transfers those antibodies through colostrum.
The system is based on the migration of red blood cells (RBC) on a membrane:
- A monoclonal antibody specific to Ca antigen has been incorporated on the membrane. This antibody will retain Ca positive RBC. A positive result is characterized by the presence of a red line in front of the Ca line.
- A monoclonal antibody specific to the equine glycophorin has been incorporated on the membrane. The control line must be positive ensuring that the test has run successfully.
Ca - : Absence of red line in front of «Ca» arrow indicates a negative reaction.2
Ca + : Presence of red line in front of "Ca" arrow indicates a positive reaction for Ca group.
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QUICK TEST Material
EQUINE QUICK TEST MATERIAL
- 1 plastic device with membrane dipstick
- 1 empty well
- 1 buffer solution
- 1 blood collector strip
- 1 schematic test manual
EQUINE QUICK TEST PACKAGING
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