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IMPORTANCE OF CROSSMATCHING
Crossmatching aims to establish a serological compatibility between the recipient and the donor. The classical technology uses an agglutination reaction to detect allo antibodies produced after a previous transfusion and/or the naturally antibodies.
Our immuno-chromatographic technology will detect the presence of immunoglobulin and/or C3 components binding to the red blood cells surface. It indicates an in vitro sensitization and can thus be used to indicate the presence of allo antibodies in pre-transfusion compatibility testing.
This test also allows to detect circulating auto antibodies in the recipient.
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THE LAB TEST XM PROCEDURE
XM - : A negative reaction in front of «XM» indicates the absence of circulating antibodies. The donor blood is compatible with the recipient.
XM + : A positive reaction (+/- to ++++) in front of «XM» indicates the presence of allo antibodies or circulating auto antibodies. The donor blood is incompatible with the recipient.
XM + WEAK : A weak reaction attest of a positive result.
3 - 3
1 BOX OF LAB TEST XM CONTAINS
- 1 tube with 5 XM membranes (1 membrane = 1 crossmatch)
- 1 wash buffer
- 1 white top buffer 1
- 1 green top buffer 2
- 5 clean test tubes
- 5 blood collectors strips
- 5 small pipettes (1ml) for serum
- 5 pipettes (3ml) for washing
- 5 results forms
ADDITIONAL MATERIAL NEEDED
LAB TEST XM PACKAGING
The LabTest xm box allows you to perform 5 crossmatch tests.
(1 xm test = 1 recipient + 1 donor)
The entire material is provided into the box, you do not need any reagents.
The only additional material needed is a centrifuge.
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